阮长耿院士对英诺华PL一11血小板分析仪的性能评价.docx 5页

阮长耿院士对英诺华PL一11血小板分析仪的性能评价作者简介：阮长耿院士任职机构：江苏省血液研究所所在科室：血液科?/user/jianjie.asp?id=168593 \t /user/_blank阮长耿，中国工程院院士，苏州大学医学教授，博士生导师。曾任苏州医学院院长，中华医学会血液学分会第七届委员会主任委员，《中华血液学杂志》总编。现任江苏省血液研究所所长，江苏省医学会副会长，《中华内科杂志》副总编，以及《中华医学杂志》、《J.?Thromb??Hemost.》、《Thromb.?Res》、《Int.J.Hematol》等国内外杂志的编委。作者：/user/index.asp?id=412822 \o 进入张有涛的主页 \t /show/_blank张有涛[1]?/user/index.asp?id=395049 \o 进入赵益明的主页 \t /show/_blank赵益明[1]?/user/index.asp?id=168593 \o 进入阮长耿的主页 \t /show/_blank阮长耿[2]?单位：苏州大学附属第一医院(江苏省血液研究所)[1]?江苏省血液研究所[2]??【摘要】目的评价PL—ll血小板分析仪的分析性能。方法用EDTA．K2及柠檬酸钠静脉抗?365医学网 转载请注明凝血，测试PL一11血小板分析仪的批内重复性、日间重复性、携带污染率、准确性及线性性能，并选择2012年2月至7月苏州大学附属第一医院门诊30位体检者的空腹柠檬酸钠静脉抗凝血与MPG．3E多功能双通道血液凝聚仪测定结果进行相关分析。结果各参数皆符合CLIA’88法案的要求。PL一11血小板分析仪批内、日间精密度的CV均5％；携带污染率1％；测定定值全血质控物，准确性满意，线性良好；测定结果与光电比浊法结果相关性分析，R!=0．9439：结论PL．1l血小板分析仪可直接使用全血动态分析血小顿聚集过程并能对血液细胞的多种组分(包括血小板和红细胞)进行定量分析，报告结果准确可靠。?365医学网 转载请注明【关键词】血小板聚集；血小板功能试验；诊断设备；评价研究?365医学网 转载请注明365医学网 转载请注明 血小板参与机体内许多生理、病理过程。测定血小板生理功能，特别是其聚集性，不仅有助于诊断某些先天性和获得性血小板缺陷所导致的出血性疾病，且在血栓性疾病发病机制、临床诊断、抗血栓疗法、监测抗血小板药物浓度等研究中有重要意义。目前，常采用光电比浊法，全血电阻法，PAFl00血小板功能仪，Verifynow系统检测血小板聚集功能。光电比浊法血小板聚集仪，在临床上的使用率超过95％，是临床应用的最多一种检测方法。以上方法存在仪器操作复杂、影响因素较多，所得结果重复性差，正常值范围宽等缺点。PL-11血小板分析仪是国产的血小板分析仪，它可直接使用全血动态分析血小板聚集过程并能对血液细胞的多种组分(包括血小板和红细胞)进行定量分析。每一测定分析可提供10项有关参数，样品结果在输出时能分别提供血小板数量变化、血小板体积变化、红细胞变化、血小板聚集曲线、血小板分布图及红细胞分布图等全面的样本信息。本研究参照美国临床实验室标准化协会(Clinical and Laboratory Standards Institute，CLSI)制定的仪器性能验证标准和美围临床实验室改进修正法案(Clinical Laboratory Improvement Amendment 88，CLIA 788法案?)制定的评价标准，对该仪器进行了分析性能评估。?365医学网 转载请注明1 材料与方法?365医学网 转载请注明1.1 仪器?365医学网 转载请注明 PL-1l血小板分析仪(南京神州英诺华医疗科技有限公司)。MPG一3E多功能双通道血液凝聚仪(上海斯隆医电设备有限公司)。BC-6800全自动血液细胞分析仪(深圳迈瑞公司)。?365医学网 转载请注明1.2 试剂?365医学网 转载请注明 PL-11血小板分析仪相关配套试剂和PLR-06血小板诱聚剂(主要组成成分为腺苷-5′-二磷酸二钠，ADP)，为南京神州英诺华医疗科技有限公司产品。BC-5600全自动血液细胞分析仪相关配套试剂，为深圳迈瑞公司产品。1.3 标本来源?柠檬酸钠抗凝静脉J衄(30份)，EDTA—K2静脉抗凝血均来自2012年2月至7月苏州大学附属第一医院门诊体检者的空腹静脉血；定值质控全m各一份由美国COULTER公司(高值批号120202，中值批号120202，低值批号120202)提供。?365医学网 转载请注明1.4 PL一1 1血小板分析仪主要性能评估方法?365医学网 转载请注明 参照CLSI文件推荐的方法进行。?365医学网 转载请注明1.4.1 批内精密度：按照CLSI的EP5一A_71文件的要求，选取EDTA—K2静脉抗凝血标本，取高、中、低值各一份，在PL-11血小板分析仪上重复测20次，分别得出PLT、MPV、RBC及MCV的CV％。365医学网 转载请注明1.4.2 日间精密度：按照CLSI的EP5一A。川文件的要求，选取EDTA．K2静脉抗凝血，取高、中、低定值全血质控物值各一份，在PL—l 1血小板分析仪上的测定，每天重复测两次，取均值，共20 d，得出PLT、MPV、RBC及MCV的CV％。?365医学网 转载请注明1.4.3 携带污染率：按CLSI EPIO—A文件要求，取EDTA．K2静脉抗凝血，选取1个高值和1个低值标本，先测高值标本，连续重复测定3次，得出H1、H2、H3；随即测低值标本，得出Ll、L2、L3。根据公式：携带污染率=(LI—L3)／(H3一L3)x 100％，其中的L1、L3及H3、L3两者相减所得的差取其绝对值，要求携带污染率1．5％。?365医学网 转载请注明1.4.4 线性分析：按EP6-A文件的方法，对系统的线性进行验证+将一高值的EDTA-K2静脉抗凝血，用生理盐水作100％、80％、60％、40％、20％、10％、5％不同浓度的稀释，测定各项参数，使用EXCEL软件计算测定值与理论值间的相关系数(r)，要求r≥O．995。?365医学网 转载请注明1.4.5 准确性：取由COULTER提供的高、中、低全血质控物各一份，采用PL-11血小板分析仪、苏州大学附属第一医院检验科所使用BC-6800全自动恤液细胞分析仪分别连续测3次，以BC-6800全自动血液细胞分析仪结果为靶值，取平均值计算偏倚，偏倚=(测定值一靶值的绝对值)／靶值X 100％。测定参数应满足1／2 CLIA′88水平(PLT≤12．5％，MPV≤12．5％，RBC≤3．5％，MCV≤3．5％)。?365医学网 转载请注明1.4.6 血小板聚集对比试验：按照CLSI EP9-A的要求，(1)血小板聚集率重复性：取1份柠檬酸钠抗凝静脉血标本，分别用PL-11血小板分析仪和MPG一3E多功能双通道I札液凝聚仪重复测定10次，分别得出最大聚集率(MAR)和平均聚集率(AAR)的CV％；(2)相关性分析：取30份柠檬酸钠抗凝静脉血标本，分别PL-11血小板分析仪和MPG-3E多功能双通道血液凝聚仪测定，每份标本2次测定间隔时间不超过5 min。结果进行相关及直线回归分析。?365医学网 转载请注明1.5 统计学分析?365医学网 转载请注明 用EXCEL软件进行统计分析，各项指标的检测结果均作算术平均值(膏)、标准差(s)、变异系数(CV)的计算；对比实验数据比较用直线回归分析。?365医学网 转载请注明2 结果?365医学网 转载请注明2.1 批内与日间精密度?365医学网 转载请注明 结果见表l。测定结果表明，PL-11血小板分析仪对血液细胞各组分的分类测定具有很高的精密度，测定所得的变异系数达到CLIA′88规定的要求。?365医学网 转载请注明365医学网 转载请注明2.2 携带污染率?365医学网 转载请注明 PL-11血小板分析仪PLT携带污染率实际测定值为0．62％；RBC携带污染率实际测定值为0.71％，均低于1％，完全满足CLIA′88规定的要求。?365医学网 转载请注明2.3 线性分析?365医学网 转载请注明 各项参数都随浓度的稀释而相应减低，PLT相关系数r=0．996；RBC相关系数r=0．997，均大于0.99。结果表明，评估选用的线性范围与CLIA′88规定的要求基本一致，能满足临床需求。?365医学网 转载请注明2.4 准确性?365医学网 转载请注明 PL-11血小板分析仪测得高、中、低值全血质控物结果与其靶值及偏倚见表2。四大参数均在偏倚范围内，其准确性可以接受。365医学网 转载请注明?365医学网 转载请注明2.5 血小板聚集对比试验?365医学网 转载请注明 (1)PL一1 1血小板分析仪与MPG一3E多功能双通道血液凝聚仪测定血小板聚集率重复性对比：PL-11血小板分析仪测定样：零的MAR和AAR的CV％分别为：6.5％和6.1％；MPG-3E多功能双通道血液凝聚仪测定样本的MAR和AAR的CV％分别为：15％和12％；(2)PL．11血小板分析仪与MPG-3E多功能双通道血液凝聚仪测定血小板聚集率相关性分析：结果见图1。PL一1 1血L／J板分析仪与MPG-3E多功能双通道血液凝聚仪测定30份样品结果比较：两种方法测定的相关性很好，R2=0.9439。?365医学网 转载请注明365医学网 转载请注明3 讨论?365医学网 转载请注明 血栓形成是血液内血小板及多种凝血因子共同作用的结果。血小板是血栓形成的首要和关键的因素。目前，对一般凝血因子的检测方法已十分成熟且广泛用于临床，而对于血小板功能以往的检测方法均不理想。因此，临床无法对高危人群及患者的血小板功能进行合理评价；对抗血小板药物治疗疗效也无法得到合理评价。测定血小板生理功能，特别是其聚集性，不仅有助于诊断某些先天性和获得性血小板缺陷所致出血性疾病，且在血栓性疾病发病机制、临床诊断、抗血栓疗法、筛选抗血小板药物、指导临床用药和监测药物浓度等研究中有重要意义。我们对PL-11血小板分析仪的精密度、携带污染率、线性、准确性及对比实验进行了测定。结果显示，英诺华PL-11血小板分析仪的线性好，基本上覆盖正常及普遍的病理范围，线性测定范围广；批内和日间CV值5％，在要求范围内，有较好的重复性；携带污染率1％，不同标本之间交叉污染小；PL-11血小板分析仪与MPG．3E多功能双通道血液凝聚仪测定结果比较，结果有较好的相关性及可比性，而且，测定结果精密度更高，变异更小。?365医学网 转载请注明转载自365医学网Writing parallel sentences highlightsWriting parallel sentences highlightsPolitical classI go to enhance the consciousness of active, dynamic, firmness.I go to enhance the strong political identity, identity theory, emotion recognition.The implementation, maintenance support, development of the overwhelming majority of the people all the benefits.That really makes people enjoy people more real, more fully, more extensive human rights.The advance of political consultation, democratic supervision, participation in politics and political system construction.The advancement of social democracy political system, standardize standardization of procedures.The implementation of self-management, self-service, self education, self supervision.- establish socialist democracy and the rule of law, freedom, peace, justice and equality.The efforts to solve the people most concerned about, the most direct benefit directly, most practical problems.That should enhance the consciousness of political power, the overall situation consciousness, suffering consciousness and sense of responsibility.The development for the people, development depends on the people, the fruits of development are shared by the people.The optimization of public resource allocation, innovation of public service system, improve the quality of public services.That respect the principal position of the people, give full play to peoples initiative, the security of the peoples rights.In. Is the mind clear, ready, moving up strong and productive.The leading cadres of the party should strengthen the party consciousness, consciousness of party spirit, conduct, and for example.The maintenance of the party and the partys ruling position, to safeguard national security, safeguard the peoples rights and interests.I go to the urban and rural communities become orderly management, perfect service, civilization and social life of the community.The construction of a reliable political, business proficiency, honest and efficient, high-quality cadres masses satisfied.The implementation of the central on the promotion of the partys seventeen seven spirit into the classroom, teaching materials, into the minds of the students.With the strengthen self construction of the CPPCC, play a coordinating relationship, gathering strength, policy suggestions, the important role of serving the overall situation.The economy must conform to the socialist economic construction, political construction, cultural construction, the construction of the new social situation, new requirements and new expectations of the people.The China characteristic socialism is the national prosperity, national rejuvenation, the peoples fundamental guarantee to happiness, is the history will be inevitable, realistic choice and direction in the future.I go to Chinese characteristics of social socialism as the great banner, to hold, as the correct way to insist, as a scientific theory to use the same as the common ideal pursuit.I go along with the reform of economic system, social structure, profound changes in the pattern of interests profound adjustment adjustment, profound changes in ideas, social contradictions into prone, multiple period.I go to extraordinary will happy to drive, very strong measures to work efficiency, extraordinary, fulfill the Chinese characteristics socialist builders, defenders of the sacred holy mission.I go to take practical action to defend the defending party leadership, defend the socialist regime, defend the socialist system Chinese characteristics, great achievements of reform and development to defend the stability, to defend the fundamental interests of the people.That this kind of big department system is conducive to straighten out the relationship, optimize the structure, improve efficiency, the formation of integrated, consistent with responsibilities, reasonable division of work, scientific decision-making, implementation of smooth smooth, powerful supervision system of administrative management system.I go to love the motherland proud, ashamed to harm the motherland; to serve the peoples pride, shame betray the people;; uphold science, with no ignorance of ignorance shame; proud of the hard work, to shame to love leisure and hate Labour Solidarity and mutual assistance; proud, ashamed to advantage;; be honest and trustworthy, to see the forget Wangyi ashamed; law-abiding proud, ashamed to lawlessness; hard to fight for glory, ashamed to extravagance and dissipation.The partys fine style of promoting stylewith folk.The adherence to democracy, openness, competition, preferred.We understand that, trust and care about the Gulf of Taiwan compatriots.The building up and perfecting the incentive mechanism, care, assistance.I go to do practical things for the masses, the solution is difficult to do good things.The Chinese country will never be selfish, and beggar thy neighbor thing.The glow of self interest, struggle, reform and innovation spirit.The adaptation to scientific governance, democratic governance, to the ruling.The development of inner-party democracy is a lot of levels, multi aspect, multi way.I go to Scientific Outlook on Development in accordance with the requirements of the assessment, evaluation and use of cadres.The advancement of the party building work of the scientific, institutionalized and standardized.The party organizations at all levels to make continuously improve creativity, cohesion and fighting capacity.In international relations, Philip triumphantly democracy, harmony, cooperation and win-win spirit.The socialist democracy political institutionalization, standardization, Cheng Cheng ordered.That adhere to the leadership of the party, the people in power, the rule of law state unity.The ability to follow and focus on performance, people accepted that principle of selection of cadres.The check to prevent and overcome the orders and prohibitions, the phenomenon of each acts in his own way.- this is our party to explore the truth, pioneering results.We will continue to implement the neighbors as good, with neighboring diplomatic policy.- create a peaceful and steady stability, equality and mutual trust, cooperation and win-win environment in the region.I go to the people strive to have real feelings, people have really measures, is really effective. The comrades of the whole party, especially leading cadres, must uphold the party spirit, re conduct, for example.New ideas, put forward that our party about the partys construction of new ideas, new conclusions.The consolidation and development of equality, unity, mutual assistance, and harmonious socialist ethnic relations.The play to the coordination of the relationship between power BSFLP forces for convergence, the important role of serving the overall situation.The idea of independence, people want a lot of activity selectivity, variability, the difference is significantly enhanced.The basic theory and adhering to and enriching, the partys basic line, basic program and basic experience,.The clear and guiding ideology to strengthen the ruling ability construction, objectives and tasks and plans.That respect the principal position of the people, play to peoples initiative, safeguard the peoples interests of the people.That must not be allowed to allow anyone in any name, in any way to separate Taiwan from the motherland.The construction of a unified, disciplined, heroic workers vanguard of the working class.The comprehensive strengthening and improving Party building is the former Kai, the same One principle runs through it all..Only reform and opening up to the development of China, socialist development, the development of the Marx doctrine.The 00 years of our party to arm Party members, with the scientific theory to guide practice, promote the work.Long term, the comrade must fully understand the anti-corruption struggle is complex, arduous.The advance of the construction of the party theory innovation, system innovation, innovation and new method innovation.The proposed knowledge in the realization of cadre team in the premise of revolution under the younger, professional industry.I go to maximize the mobilization of the enthusiasm of product, Party organizations and members at all levels of the initiative and creativity.The overall design thinking of the theory and practice of the construction of the partys prospective, forward-looking, strategic issues.From 1983 - from within the 3 years of the partys ideology, style and organization for an overhaul.- such as how to further open up the case to adapt to the new requirements, learning new knowledge and new skills, exercise.The party put forward clearly the party building is on their own, do not grasp the party building is dereliction of duty, unable to grasp the party building is incompetent.The expansion of socialist democracy, the construction of socialist rule of law governing country, the development of the socialist political civilization.That our party is against publicity masses, organizing the masses, relying on the masses all started from victory to victory.Give full play to the grass-roots party organization, promoting development, serving the people, unite gather people, promote harmony.The promotion of relations between political parties, ethnic relations, religious relations, hierarchical relations, the harmonious relationship between the overseas compatriots.I go for a modern, facing the world, facing the future of socialism China stand in the east of the world.The formalism, bureaucracy issues more prominent, extravagance, negative corruption is still quite serious.In the reform and improve the partys leadership and governance, new progress has been made in the system of leadership system and work.Lenin believes that the democracy within the party, highly focused on the iron discipline is an important foundation to maintain the unity of the partys hold.The 30 year that the construction of the party is in the world situation, the party situation, the big background of major and profound changes in the.That our party has established the symptoms, comprehensive treatment, prevention and punishment and prevention, focusing on prevention of anti-corruption corruption strategy.In the guiding ideology and policy and major principles, the whole Party must maintain a high degree of consistency.The reduced levels of administration, reduce administrative costs, and strive to resolve overlapping responsibilities, cross, each department acting on its own.The China peoples appearance, Chinese socialist outlook has undergone historic changes China communist spirit.The enhancement of basic physical theory, study and implement the partys basic line, basic program and basic experience of the consciousness and firmness.The effective resist money worship, hedonism, extreme individualism and erosion of corruption of the body body of the party.- all these, caused by the global economic situation has undergone major changes, not without interest before Princess Bureau and the security pattern.The separate, in party and government decentralization, streamlining mechanism, strengthening the construction of democracy and legal system and adopted some reform measures.The courage to change, innovation, permanent stagnation, never rigid, I become our partys long-term adhere to the governing of the road.That clearly put in real practice especially in difficult environment, the contradiction between the shield, prominent local refining and difficult exercise training of cadres.The building of socialist market economy, socialist democracy, socialist advanced culture, socialist harmonious society.That we will unswervingly implement the principle of one country two systems, Hong Kong, Macao and a high degree of autonomy for the policy.The reform and opening up is the characteristics of this period is the most vivid, the most remarkable achievement is the rapid development of the times, is a symbol of the most prominent.I go to the construction of anti-corruption and the partys ideological construction, organization construction, style construction, system construction coordinate, constitute the overall arrangement of Party Construction of the party.There is one generation after another to go to Chinese Communist successor, not afraid of sacrifice, hard fighting, forge ahead, to lay the China in todays situation.I go to the party construction work in the history of international comparison, observation, grasp the reality of a wide field of vision, deepen the understanding, improve the level of.The partys grassroots organization undertakes to unite the people, organize the masses, educate the masses, the partys line principles and policies to the important responsibility of basic level.The people of all ethnic groups that consolidate the unity, strengthen the great unity of the Chinese people at home and abroad. China people in promoting the unity with the peoples of the world.The legislation must adhere to the party for the public and governing for the people, to achieve now, to maintain a good development, the overwhelming majority of people as the fundamental interests of the partys nuclear core value.The recovery of our party in everything from the reality, theory with practice, seeking truth from facts, in practice practice testing and developing truth truth ideological line.That we realize modernization of the motherland, complete national unity, safeguard world peace and promote common development of the three major historical tasks: full of confidence.How to strengthen the party construction of the ruling party, consolidate the ruling partys position, to complete the partys mission, Ma Max and Engels put forward many important thoughts.The party hold the ruling position is not innate, but also not permanent, past have not equal to now have, now have not always equal.The seriously solve the existing party organizations and Party members in the ideological confusion, organization Huan do bad work style, outstanding problems such as lax discipline process and achieved significant results.The party in the country at or above the county level leadership guide team, leadership and cadres to carry out to say study, talk politics, righteousness Qi party spirit education as the main content.The party organizations at all levels of organization and Party members and cadres to firmly grasp the one center, two basic points between interconnected, interdependent, indivisible relationship.The hard to stick with the system steward, all right, tube, establish and improve the decision-making power, executive power and supervision power mutually control the power structure and operation mechanism and coordination with each other.That many of the members of the Communist Party of Buweijianxian, heavy responsibilities, Sheshesheng forget the death, rushed in front of the full show in the new period of the Communist Party of good character and good times style.The Ma Max doctrine only with national conditions combined with the progress of development, with the times, and peoples common destiny, can shine strong vitality, creativity and appeal.? This 30 year is the partys theoretical innovation results were more and more party members and the masses of the study, the acceptance, the master, the use of the theoretical results into a huge amount of material power.The changing job functions, straightening out relations, optimizing the structure, improving efficiency, formation, responsibilities consistent, rational division of labor, scientific decision-making, execution for smooth, strong supervision and administrative management system.I go to the party members especially leading cadres strict requirements, strict education, strict management, strict supervision and supervision; in the inner life of party spirit,, in principle, promote righteousness, crooked against wind.The real political rely on reliable, have the ability to work, the style of the wind hard life, peoples trust, to good at leading scientific development show outstanding cadres at all levels to leadership positions.The general interests of our Taiwan compatriots were things beneficial to the maintenance of peace in the Taiwan Strait Taiwan all things, all to promote the peaceful reunification of the motherland do good things, we will try our best to do well.- sincerely listen to their whirring sound, truly reflect the aspirations of the masses, the truth really concerned about the sufferings of the masses, for the masses of all good things, do solid work, do the power used for the people, love the people, and work for the people.I go on one Chinese principle will not waver, and strive for the mediocre unified effort and never give up, to carry out thorough hopes on the Taiwan people policy will never change, opposing secessionist activities will not crack compromise.There is definitely not to explore and answer what is socialism, how to build socialism, building what kind of party, how to build it, and what kind of development, how the development of major theoretical and practical problems.In accordance with the adhere to the standards, assure quality, improve the structure, Shen retransmission development policy, conscientiously do a good job in the workers, peasants, intellectuals, exhibition development of Party members and cadres in the army advanced elements of the work.In the basis of chaos dialedrandomly re established Ma Maxs ideological line, political line and organizational line, with great political and theoretical courage of scientific evaluation of Comrade Mao Zedong and Mao Zedong thought.The use China characteristics socialist common ideal cohesion to God the national spirit with patriotism as the core of the reform and innovation as the core of the time spirit inspire morale, lead the fashion with a socialist concept of honor and disgrace.That any one party, regardless of the strength of more powerful, qualified old ruling time long, if conservative, solid step self seal, ossified, lazy, the creativity will failure, vitality will stop.The building of the party has become the party for the public, the executive party, become the scientific ruling, democratic ruling, ruling according to law, and be realistic and pragmatic, pioneering and innovative, diligent, efficient, honest and clean of the ruling party.I go to improve the democratic system, enrich the forms of democracy, expand democratic channels, to carry out democratic election, democratic decision-making, democratic management, democratic supervision, and safeguard the peoples right to know, right to participate, right of expression, the right of supervision.The Deng Xiaoping theory, Three Represents important thought and the scientific outlook on development and other major strategic thoughts with mutual cohesion, coalescence, line bearing and advancing with the times, together constitute the China country socialist theoretical system.There is clearly to adhere to the integrity and both focus on performance, recognized by the masses of the people, adhere to the principle of merit, decent for a line of justice, adhere to scientific development, focusing on character, advocating is dry, pay attention to the grassroots, to encourage innovation, recognized by the masses of people oriented.In order to keep the flesh and blood ties between the party and the peoples blood as the core, to build high quality cadres as the key, focus on reform and improve the partys leadership system and working mechanism, to strengthen the partys grassroots organizations and Party members base construction as the foundation, strengthen the Party Construction.The comrades want to cherish, long-term adherence and development of the party through a China by the hard characteristic socialist road and Chinese characteristics of socialist theory system, emancipating the mind, seeking truth from facts, and keep pace with the times, the courage to change, innovation, never rigid, never stagnant.The ideological liberation is a magic weapon for the development of socialist Chinese righteousness, the reform and opening up is the development of strong power, China socialism scientific development and social harmony are basic requirements for the development of socialism Chinese characteristics, comprehensively building a moderately well-off society society is the party and the state to reach two, two, annual goals.The picture according to the democracy and the rule of law, fairness and justice, honesty and faithful love, full of vitality, stability and order to order requirements and jointly build a harmonious coexistence of man and nature, shared principles, efforts to solve the people most happy, themore than flow into the city, Apart from the Riverside road, old road network, other sections are nearing saturation, South Gate Bridge and ends at the intersection of rongzhou bridge f level of service. Xufu Road South and rongzhou road is saturated. The average speed of the network as a whole is low, most of the road speed is less than 20km/hWriting parallel sentences highlightsWriting parallel sentences highlightsPolitical classI go to enhance the consciousness of active, dynamic, firmness.I go to enhance the strong political identity, identity theory, emotion recognition.The implementation, maintenance support, development of the overwhelming majority of the people all the benefits.That really makes people enjoy people more real, more fully, more extensive human rights.The advance of political consultation, democratic supervision, participation in politics and political system construction.The advancement of social democracy political system, standardize standardization of procedures.The implementation of self-management, self-service, self education, self supervision.- establish socialist democracy and the rule of law, freedom, peace, justice and equality.The efforts to solve the people most concerned about, the most direct benefit directly, most practical problems.That should enhance the consciousness of political power, the overall situation consciousness, suffering consciousness and sense of responsibility.The development for the people, development depends on the people, the fruits of development are shared by the people.The optimization of public resource allocation, innovation of public service system, improve the quality of public services.That respect the principal position of the people, give full play to peoples initiative, the security of the peoples rights.In. Is the mind clear, ready, moving up strong and productive.The leading cadres of the party should strengthen the party consciousness, consciousness of party spirit, conduct, and for example.The maintenance of the party and the partys ruling position, to safeguard national security, safeguard the peoples rights and interests.I go to the urban and rural communities become orderly management, perfect service, civilization and social life of the community.The construction of a reliable political, business proficiency, honest and efficient, high-quality cadres masses satisfied.The implementation of the central on the promotion of the partys seventeen seven spirit into the classroom, teaching materials, into the minds of the students.With the strengthen self construction of the CPPCC, play a coordinating relationship, gathering strength, policy suggestions, the important role of serving the overall situation.The economy must conform to the socialist economic construction, political construction, cultural construction, the construction of the new social situation, new requirements and new expectations of the people.The China characteristic socialism is the national prosperity, national rejuvenation, the peoples fundamental guarantee to happiness, is the history will be inevitable, realistic choice and direction in the future.I go to Chinese characteristics of social socialism as the great banner, to hold, as the correct way to insist, as a scientific theory to use the same as the common ideal pursuit.I go along with the reform of economic system, social structure, profound changes in the pattern of interests profound adjustment adjustment, profound changes in ideas, social contradictions into prone, multiple period.I go to extraordinary will happy to drive, very strong measures to work efficiency, extraordinary, fulfill the Chinese characteristics socialist builders, defenders of the sacred holy mission.I go to take practical action to defend the defending party leadership, defend the socialist regime, defend the socialist system Chinese characteristics, great achievements of reform and development to defend the stability, to defend the fundamental interests of the people.That this kind of big department system is conducive to straighten out the relationship, optimize the structure, improve efficiency, the formation of integrated, consistent with responsibilities, reasonable division of work, scientific decision-making, implementation of smooth smooth, powerful supervision system of administrative management system.I go to love the motherland proud, ashamed to harm the motherland; to serve the peoples pride, shame betray the people;; uphold science, with no ignorance of ignorance shame; proud of the hard work, to shame to love leisure and hate Labour Solidarity and mutual assistance; proud, ashamed to advantage;; be honest and trustworthy, to see the forget Wangyi ashamed; law-abiding proud, ashamed to lawlessness; hard to fight for glory, ashamed to extravagance and dissipation.The partys fine style of promo