抗体名称 | Anti-PGC1 Alpha/PPARGC1A Antibody |
指标别名 | LEM6;PGC1;PGC1A;PPARGC1;PPARGC1A;PPARGC-1-alpha;PGC-1-alpha |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | PPARGC1A |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human PGC1 alpha |
实际分子量 | 113KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism.This protein interacts with PPARgamma,which permits the interaction of this protein with multiple transcription factors.This protein can interact with,and regulate the activities of,cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs).It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis,and is a major factor that regulates muscle fiber type determination.This protein may be also involved in controlling blood pressure,regulating cellular cholesterol homoeostasis,and the development of obesity. |
Uniprot ID | |